Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28064067 | 0.88 | KDM4E (0.40) | KDM4EALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL28088219 | 0.85 | PPARG (0.36) | TSHRSMN1; SMN2 | |
| SCHEMBL28064063 | 0.84 | KDM4E (0.40) | KDM4EALDH1A1TDP1ATMTSHR | |
| SCHEMBL2228066 | 0.83 | LMNA (0.41) | KDM4EALDH1A1TDP1NPSR1ATM | |
| SCHEMBL28064102 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1LMNATP53MEN1 | |
| SCHEMBL28064203 | 0.79 | PPARG (0.46) | TSHR | |
| SCHEMBL28064084 | 0.78 | TEAD1 (0.47) | ALDH1A1TDP1LMNA | |
| SCHEMBL28088194 | 0.78 | PPARG (0.40) | KDM4EALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL28064163 | 0.77 | ALDH1A1 (0.38) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL28064060 | 0.77 | LTA4H (0.39) | ALDH1A1NPSR1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | claimed |
| CN-105837565-A | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | 赛诺菲 | 2016-08-10 | — | — | CN | disclosed |
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | disclosed |