Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.34 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28064084 | 0.86 | TEAD1 (0.47) | LMNATEAD1TEAD3ALDH1A1 | |
| SCHEMBL28064081 | 0.86 | PTGDR2 (0.40) | IDO1SSTR4SLC6A2SLC6A4MEN1 | |
| SCHEMBL28064163 | 0.85 | ALDH1A1 (0.38) | KDM4EIDO1MEN1KMT2AHTR7 | |
| SCHEMBL28064067 | 0.83 | KDM4E (0.40) | KDM4EMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL28064087 | 0.83 | TEAD1 (0.44) | TEAD1TEAD3 | |
| SCHEMBL28064086 | 0.83 | LTA4H (0.39) | MEN1KMT2ATEAD1TEAD3 | |
| SCHEMBL28064079 | 0.82 | KDM4E (0.39) | KDM4EMEN1KMT2ALMNATP53 | |
| SCHEMBL28064077 | 0.82 | KDM4E (0.44) | KDM4ESSTR4MEN1KMT2AHTR7 | |
| SCHEMBL28088153 | 0.82 | HRH3 (0.37) | KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL2228770 | 0.81 | GRIN2B (0.43) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | claimed |
| CN-105837565-A | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | 赛诺菲 | 2016-08-10 | — | — | CN | disclosed |
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | disclosed |