Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | KRAS | P01116 | 5/20 | 0.34 |
| ▸ | BCL2 | P10415 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9091990 | 0.81 | HTR2A (0.48) | DUTHTR7HTR2AHTR2CKRAS | |
| Ethoxycarbonyl Group SCHEMBL27738749 | 0.74 | CYP2A6 (0.49) | HTR7HTR2AHTR2CKRASMCL1 | |
| SCHEMBL6260801 | 0.74 | DUT (0.52) | DUTHTR2AHTR2CBCL2MCL1 | |
| SCHEMBL9092781 | 0.73 | HTR7 (0.49) | DUTHTR7HTR2AHTR2CMCL1 | |
| SCHEMBL9093439 | 0.73 | DUT (0.51) | DUTBCL2MCL1NR1H2PPARA | |
| Ethoxycarbonyl Group SCHEMBL28294128 | 0.73 | HTR2A (0.44) | HTR7HTR2AHTR2CKRASNTSR1 | |
| SCHEMBL28064107 | 0.72 | DUT (0.37) | DUT | |
| SCHEMBL18856950 | 0.71 | HTR2A (0.55) | HTR7HTR2AHTR2CNTSR1PLG | |
| SCHEMBL6029849 | 0.71 | CDK4 (0.57) | DUTHTR2AHTR2C | |
| SCHEMBL9940446 | 0.70 | SMN1; SMN2 (0.42) | MCL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103347875-B | As the indoles of respiratory syncytial virus antiviral agent | JANSSEN R&D IRELAND (IE) | 2016-03-30 | — | — | CN | disclosed |