Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 6/20 | 0.34 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.33 |
| ▸ | GSK3B | P49841 | 3/20 | 0.32 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | QPCT | Q16769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28294127 | 0.73 | SMN1; SMN2 (0.41) | CYP19A1 | |
| SCHEMBL27738748 | 0.73 | CYP19A1 (0.41) | CYP19A1GSK3BABCC2 | |
| Ethoxycarbonyl Group SCHEMBL28064108 | 0.72 | DUT (0.43) | DUT | |
| SCHEMBL27782147 | 0.71 | EGFR (0.42) | IDO1CYP19A1 | |
| SCHEMBL27417452 | 0.69 | CNR2 (0.40) | CNR2 | |
| SCHEMBL28038696 | 0.67 | PSEN1 (0.37) | CNR2CYP19A1 | |
| SCHEMBL2819961 | 0.67 | ALDH1A1 (0.50) | DUT | |
| SCHEMBL27449972 | 0.67 | PTGER4 (0.38) | CNR2CYP19A1CNR1 | |
| SCHEMBL22152008 | 0.65 | DUT (0.40) | DUTCNR2GSK3BCNR1QPCT | |
| SCHEMBL9091856 | 0.65 | HTR1D (0.43) | DUTGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103347875-B | As the indoles of respiratory syncytial virus antiviral agent | JANSSEN R&D IRELAND (IE) | 2016-03-30 | — | — | CN | disclosed |