Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.54 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10787566 | 0.83 | PTGS1 (0.56) | MAOBKDM4EMEN1MAPTKMT2A | |
| SCHEMBL6065347 | 0.82 | MAOB (0.58) | MAOBKDM4EMEN1MAPTKMT2A | |
| SCHEMBL15059054 | 0.81 | LMNA (0.58) | MAOBKDM4EMEN1MAPTKMT2A | |
| SCHEMBL9179800 | 0.81 | ALOX5 (0.53) | MAOBKDM4EMEN1MAPTKMT2A | |
| SCHEMBL5570579 | 0.80 | CYP2C19 (0.47) | MAPTKMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL7899580 | 0.80 | CYP2C19 (0.47) | MAPTKMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL584028 | 0.80 | CYP2C19 (0.47) | MAPTKMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL6036170 | 0.80 | MAOB (0.59) | MAOBKDM4EMEN1MAPTKMT2A | |
| SCHEMBL10891366 | 0.80 | MAOB (0.56) | MAOBKDM4EMEN1MAPTKMT2A | |
| SCHEMBL9232775 | 0.79 | PKM (0.59) | MAOBKDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669423-A | New synthesis method of two enantiomers of 4-(4-(benzyloxy)phenyl)-2-hydroxybutyric acid | 江西科技师范大学 | 2016-06-15 | — | — | CN | claimed |