Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.57 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.57 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.57 |
| ▸ | RXRA | P19793 | 1/20 | 0.56 |
| ▸ | RXRB | P28702 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 4/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5383914 | 0.87 | NPC1 (0.56) | MAOBNR4A2NR4A1NR4A3RXRA | |
| SCHEMBL6036170 | 0.86 | MAOB (0.59) | MAOBNR4A2NR4A1NR4A3RXRA | |
| SCHEMBL9232775 | 0.84 | PKM (0.59) | MAOBNR4A2NR4A1NR4A3RXRA | |
| SCHEMBL9232869 | 0.84 | PKM (0.59) | MAOBNR4A2NR4A1NR4A3RXRA | |
| SCHEMBL9232872 | 0.84 | PKM (0.59) | MAOBNR4A2NR4A1NR4A3RXRA | |
| SCHEMBL9265354 | 0.84 | PKM (0.58) | MAOBNR4A2NR4A1NR4A3KDM4E | |
| SCHEMBL4602365 | 0.83 | LMNA (0.61) | MAOBNR4A2NR4A1NR4A3RXRA | |
| SCHEMBL28064117 | 0.82 | MAOB (0.55) | MAOBNR4A2NR4A1NR4A3RXRA | |
| SCHEMBL6261737 | 0.82 | MAOB (0.55) | MAOBNR4A2NR4A1NR4A3RXRA | |
| SCHEMBL17024339 | 0.81 | LMNA (0.58) | MAOBNR4A2NR4A1NR4A3RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636164-A2 | PROCESS FOR PREPARING 3-ARYL-2-HYDROXY PROPANOIC ACID DERIVATIVES WITHOUT RESOLUTION | CADILA HEALTHCARE LTD. (IN) | 2006-03-22 | — | — | EP | disclosed |
| WO-2005019152-A2 | PROCESS FOR PREPARING 3-ARYL-2-HYDROXY PROPANOIC ACID DERIVATIVES WITHOUT RESOLUTION | CADILA HEALTHCARE LIMITED (IN) | 2005-03-03 | — | — | WO | disclosed |
| CN-1582279-A | Peroxisome-activated receptor agonists | LILLY CO ELI (US) | 2005-02-16 | — | — | CN | disclosed |