Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | SNCA | P37840 | 2/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16961402 | 0.79 | PDK1 (0.42) | CYP1A2SNCAPDK1ALDH1A1TSHR | |
| SCHEMBL27897142 | 0.79 | CYP1A2 (0.39) | CYP1A2SNCAPDK1ALDH1A1TSHR | |
| SCHEMBL16961286 | 0.79 | PDK1 (0.51) | CYP1A2SNCAPDK1ALDH1A1TSHR | |
| SCHEMBL7534585 | 0.77 | CYP1A2 (0.40) | CYP1A2SNCAPDK1ALDH1A1TSHR | |
| SCHEMBL7530158 | 0.77 | CYP1A2 (0.40) | CYP1A2SNCAPDK1ALDH1A1TSHR | |
| SCHEMBL28531178 | 0.77 | CYP1A2 (0.44) | CYP1A2SNCAPDK1ALDH1A1TSHR | |
| SCHEMBL28040575 | 0.76 | CASP6 (0.58) | PDK1TSHRKMT2ALMNA | |
| SCHEMBL28160982 | 0.75 | ALDH1A1 (0.58) | ALDH1A1TSHRTDP1CYP3A4HPGD | |
| SCHEMBL28046371 | 0.73 | SLC6A4 (0.40) | CYP1A2SNCAPDK1ALDH1A1TSHR | |
| SCHEMBL5178027 | 0.72 | TSHR (0.56) | CYP1A2ALDH1A1TSHRTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105579457-A | Substituted N-biphenyl-3-acetylamino-benzamides and N- [3- (acetylamino) phenyl ] -biphenyl-carboxamides and their use as WNT signaling pathway inhibitors | Bayer Pharma AG | 2016-05-11 | — | — | CN | disclosed |