Methacrylic Acid

Methacrylic Acid

SCHEMBL28064404

C=C(C)C(=O)O.C=C(Cc1ccccc1)C(=O)OC.C=C(OC)C(=O)O

nearest known ligand 0.43

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
ALDH1A1 P00352 3/20 0.41
RAB9A P51151 3/20 0.41
MAPT P10636 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NPC1 O15118 3/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CNR2 P34972 1/20 0.40
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
USP2 O75604 1/20 0.39
PLAU P00749 1/20 0.39
ELANE P08246 1/20 0.39
AKR1B1 P15121 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
MAPK8 P45983 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL27594680 0.94 ALDH1A1 (0.43) CES2CES1ALDH1A1RAB9AMAPT
Methacrylic Acid SCHEMBL28211144 0.88 ALDH1A1 (0.39) CES2CES1ALDH1A1RAB9AMAPT
SCHEMBL28118587 0.87 CES2 (0.48) CES2CES1ALDH1A1RAB9AMAPT
SCHEMBL1666500 0.87 CES2 (0.48) CES2CES1ALDH1A1RAB9AMAPT
SCHEMBL28076128 0.85 ALDH1A1 (0.41) CES2CES1ALDH1A1RAB9AMAPT
Hydrochloric Acid SCHEMBL28053659 0.84 CES2 (0.45) CES2CES1ALDH1A1RAB9AMAPT
SCHEMBL28321505 0.84 L3MBTL1 (0.41) CES2CES1ALDH1A1RAB9AMAPT
SCHEMBL28227538 0.82 RAB9A (0.42) CES2CES1ALDH1A1RAB9AMAPT
SCHEMBL28327231 0.81 ALDH1A1 (0.43) CES2CES1ALDH1A1RAB9AMAPT
SCHEMBL29189525 0.81 ALDH1A1 (0.40) CES2CES1ALDH1A1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106189583-A One is applied to 25 type passenger vehicle water based shop primer and preparation method thereof 成都拜迪新材料有限公司 2016-12-07 CN disclosed
CN-103906777-B Copolymer 日本曹达株式会社 2016-09-14 CN disclosed
CN-104159963-B It is combined with organic mineral complex and the formation compositions thereof of olefin polymer 日本曹达株式会社 2016-06-29 CN disclosed