Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | HTT | P42858 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL205059 | 0.86 | MEN1 (1.00) | MEN1KMT2AHTTLMNAGPR35 | |
| SCHEMBL12095462 | 0.84 | MEN1 (0.95) | MEN1KMT2AHTTLMNAGPR35 | |
| SCHEMBL12933087 | 0.78 | MEN1 (0.84) | MEN1KMT2AHTTLMNAGPR35 | |
| SCHEMBL5654609 | 0.78 | GPR35 (0.66) | MEN1KMT2AHTTLMNAGPR35 | |
| SCHEMBL482509 | 0.77 | MEN1 (0.74) | MEN1KMT2AHTTLMNAGPR35 | |
| SCHEMBL980505 | 0.77 | ALDH1A1 (0.47) | MEN1KMT2AHTTLMNAGPR35 | |
| SCHEMBL28104445 | 0.77 | MEN1 (0.48) | MEN1KMT2AHTTLMNAGPR35 | |
| SCHEMBL27946670 | 0.77 | ALDH1A1 (0.65) | MEN1KMT2AHTTLMNAGPR35 | |
| SCHEMBL29173960 | 0.74 | KMT2A (0.69) | MEN1KMT2AHTTLMNAGPR35 | |
| SCHEMBL9550826 | 0.74 | MEN1 (0.69) | MEN1KMT2AHTTLMNAGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105440029-A | 5-(1,2,4-Triazol-1-yl)-2-benzylaminothiazole derivatives and application thereof as antitumor drug | UNIV HUNAN | 2016-03-30 | — | — | CN | claimed |