Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL994720 | 0.86 | MEN1 (0.56) | ALDH1A1CYP3A4MEN1KMT2AHTT | |
| SCHEMBL17132338 | 0.80 | ALDH1A1 (0.62) | ALDH1A1CYP3A4MEN1KMT2AHTT | |
| SCHEMBL8329477 | 0.78 | GPR35 (0.66) | ALDH1A1CYP3A4MEN1KMT2AHTT | |
| SCHEMBL5654609 | 0.78 | GPR35 (0.66) | ALDH1A1CYP3A4MEN1KMT2AHTT | |
| SCHEMBL13735277 | 0.77 | ALDH1A1 (0.65) | ALDH1A1CYP3A4MEN1KMT2AHTT | |
| SCHEMBL14744103 | 0.77 | GPR35 (0.65) | ALDH1A1CYP3A4MEN1KMT2AHTT | |
| SCHEMBL11942497 | 0.77 | ALDH1A1 (0.47) | ALDH1A1CYP3A4MEN1KMT2AHTT | |
| SCHEMBL8327908 | 0.77 | GPR35 (0.65) | ALDH1A1CYP3A4MEN1KMT2AHTT | |
| SCHEMBL482509 | 0.77 | MEN1 (0.74) | ALDH1A1CYP3A4MEN1KMT2AHTT | |
| SCHEMBL4660845 | 0.77 | ALDH1A1 (0.48) | ALDH1A1CYP3A4MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009649-A1 | METHOD FOR PREPARING 2-(n-BUTYL)-5-NITROBENZOFURAN | FINORGA | 2011-01-13 | — | — | US | disclosed |
| US-4187233-A | Pressure-sensitive or heat-sensitive recording material and novel 2,2-diarylchromeno compounds used therein | CIBA-GEIGY CORPORATION (US) | 1980-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009649-A1 | METHOD FOR PREPARING 2-(n-BUTYL)-5-NITROBENZOFURAN | CYP8B1, NISCH, CBR3 | ALDH1A1 903/4885CYP3A4 98/4885MEN1 4245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.