SCHEMBL28064610

SCHEMBL28064610

C[Si](C)(C)OC(=O)c1ccccc1C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.56
ALOX15 P16050 1/20 0.56
AKR1C3 P42330 2/20 0.45
KDM4E B2RXH2 4/20 0.44
HPGD P15428 3/20 0.44
HSD17B10 Q99714 3/20 0.44
TSHR P16473 2/20 0.44
HMGB1 P09429 2/20 0.44
NAPRT Q6XQN6 2/20 0.44
ESR1 P03372 1/20 0.44
ITGB3 P05106 1/20 0.44
ITGA2B P08514 1/20 0.44
GGT1 P19440 1/20 0.44
PTGS1 P23219 1/20 0.44
PTGS2 P35354 1/20 0.44
BLM P54132 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16004864 0.92 TSHR (0.50) ALDH1A1ALOX15KDM4EHSD17B10TSHR
Potassium SCHEMBL30901224 0.90 TSHR (0.48) ALDH1A1ALOX15KDM4EHSD17B10TSHR
SCHEMBL30778085 0.80 LMNA (0.62) ALDH1A1ALOX15KDM4EHPGDHSD17B10
SCHEMBL19858511 0.79 TSHR (0.75) ALDH1A1KDM4EHSD17B10TSHRTDP1
SCHEMBL27352924 0.78 PTPN2 (0.47) ALDH1A1ALOX15KDM4EHSD17B10TSHR
SCHEMBL11092121 0.78 CES2 (0.52) ALDH1A1HPGDESR1SMN1; SMN2LMNA
Phthalic Acid SCHEMBL28429524 0.78 ALDH1A1 (0.74) ALDH1A1ALOX15AKR1C3KDM4EHPGD
SCHEMBL40534 0.77 ALDH1A1 (0.64) ALDH1A1ALOX15AKR1C3KDM4EHPGD
SCHEMBL31440979 0.77 ALDH1A1 (0.64) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Dimethyl Phthalate SCHEMBL9436120 0.77 ALDH1A1 (0.64) ALDH1A1ALOX15AKR1C3KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111269650-B Organic silicon high-temperature-resistant anticorrosive paint and preparation method thereof 厦门中构新材料科技股份有限公司 2021-08-03 CN claimed
CN-111269650-A Organic silicon high-temperature-resistant anticorrosive paint and preparation method thereof 厦门中构新材料科技股份有限公司 2020-06-12 CN claimed
CN-111269650-B Organic silicon high-temperature-resistant anticorrosive paint and preparation method thereof 厦门中构新材料科技股份有限公司 2021-08-03 CN disclosed
CN-111269650-A Organic silicon high-temperature-resistant anticorrosive paint and preparation method thereof 厦门中构新材料科技股份有限公司 2020-06-12 CN disclosed
CN-105556732-B Electrolyte and lithium rechargeable battery 旭化成株式会社 2018-04-03 CN disclosed
CN-105556732-A Electrolyte and lithium-ion secondary battery ASAHI CHEMICAL IND 2016-05-04 CN disclosed