Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 8/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1384146 | 0.77 | NR3C2 (0.59) | NR3C2 | |
| SCHEMBL3302698 | 0.72 | TAS2R14 (0.47) | HSD11B1CTNNB1WNT3A | |
| SCHEMBL29410865 | 0.72 | TAS2R14 (0.47) | HSD11B1CTNNB1WNT3A | |
| SCHEMBL30889359 | 0.71 | KDM4E (0.45) | CTNNB1WNT3A | |
| SCHEMBL31407282 | 0.71 | PARP1 (0.46) | HSD11B1CTNNB1WNT3ASMN1; SMN2 | |
| SCHEMBL16549389 | 0.69 | KDM4E (0.56) | — | |
| SCHEMBL2024463 | 0.69 | NR4A2 (0.47) | KMT2ASMN1; SMN2 | |
| SCHEMBL29575721 | 0.69 | NR4A2 (0.47) | KMT2ASMN1; SMN2 | |
| SCHEMBL30038582 | 0.68 | CFTR (0.46) | NR3C2 | |
| SCHEMBL2358001 | 0.67 | NR3C2 (0.60) | NR3C2PTGS2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105473552-A | Method for producing pyrrole derivative, and intermediate thereof | DAIICHI SANKYO CO LTD | 2016-04-06 | — | — | CN | disclosed |