SCHEMBL28064877

SCHEMBL28064877

CCC(=O)ONC(=O)[C@H](C)N

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC15A1 P46059 1/20 0.40
DPP4 P27487 1/20 0.38
DPP8 Q6V1X1 1/20 0.37
DPP7 Q9UHL4 1/20 0.37
NAAA Q02083 1/20 0.33
PAX8 Q06710 1/20 0.33
XIAP P98170 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
LTA4H P09960 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
CTRB1 P17538 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21611684 1.00 SLC15A1 (0.40) SLC15A1DPP4DPP8DPP7NAAA
SCHEMBL21158809 0.84 NAAA (0.34) NAAAMEN1KMT2AMGAMGAA
SCHEMBL20138652 0.83 ALDH1A1 (0.43) SLC15A1DPP4DPP8DPP7PAX8
SCHEMBL27903585 0.79 DPP7 (0.40) SLC15A1DPP4DPP7NAAA
SCHEMBL27500430 0.78 TSHR (0.46) NAAAMEN1KMT2AALDH1A1
SCHEMBL28310176 0.78 DPP4 (0.34) SLC15A1DPP4DPP8DPP7PAX8
SCHEMBL27886795 0.76 ANPEP (0.34)
SCHEMBL27478374 0.76
SCHEMBL28969882 0.75 ALDH1A1 (0.46) SLC15A1DPP4DPP8DPP7MGAM
SCHEMBL28102654 0.75 SLC15A1 (0.32) SLC15A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116143678-A Conjugate linker, cell-binding molecule-drug conjugate containing the same, and preparation and application thereof 杭州多禧生物科技有限公司 2023-05-23 CN disclosed
CN-110099682-A Coupled connector, cell binding molecule-drug conjugate containing same, and preparation and application thereof 杭州多禧生物科技有限公司 2019-08-06 CN disclosed
CN-105510497-A Quantitative detection method of L-alanyl-L-alanine JING JING PHARMACEUTICAL CO LTD 2016-04-20 CN disclosed