Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849330 | 0.86 | MGAM (0.35) | MEN1KMT2AMGAMGAASI | |
| SCHEMBL21611684 | 0.84 | SLC15A1 (0.40) | NAAAMEN1KMT2AMGAMGAA | |
| SCHEMBL28064877 | 0.84 | SLC15A1 (0.40) | NAAAMEN1KMT2AMGAMGAA | |
| SCHEMBL27500430 | 0.80 | TSHR (0.46) | NAAAMEN1KMT2AALDH1A1 | |
| SCHEMBL9849332 | 0.80 | ALDH1A1 (0.33) | MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL27903585 | 0.77 | DPP7 (0.40) | NAAA | |
| SCHEMBL13268373 | 0.75 | — | — | |
| SCHEMBL29063188 | 0.74 | CA2 (0.50) | NAAA | |
| SCHEMBL10363703 | 0.74 | — | — | |
| SCHEMBL27886795 | 0.74 | ANPEP (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3908571-A1 | KETAMINE DERIVATIVES AND COMPOSITIONS THEREOF | XWPharma Ltd. (KY) | 2021-11-17 | — | — | EP | disclosed |
| EP-3737665-A1 | PRODRUGS OF KETAMINE, COMPOSITIONS AND USES THEREOF | XW Laboratories Inc. (KY) | 2020-11-18 | — | — | EP | disclosed |
| WO-2020143198-A1 | KETAMINE DERIVATIVES AND COMPOSITIONS THEREOF | XW LABORATORIES INC. (KY) | 2020-07-16 | — | — | WO | disclosed |
| WO-2019137381-A1 | PRODRUGS OF KETAMINE, COMPOSITIONS AND USES THEREOF | XW LABORATORIES, INC. (CN) | 2019-07-18 | — | — | WO | disclosed |