Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 8/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28065027 | 0.78 | RIPK1 (0.50) | RIPK1KDM1A | |
| SCHEMBL28209964 | 0.76 | KDM1A (0.43) | RIPK1KDM1A | |
| SCHEMBL28065026 | 0.72 | RIPK1 (0.44) | RIPK1KDM1A | |
| SCHEMBL28064896 | 0.69 | RIPK1 (0.48) | RIPK1ACHE | |
| SCHEMBL28209962 | 0.69 | RIPK1 (0.48) | RIPK1ACHE | |
| SCHEMBL28063655 | 0.69 | RIPK1 (0.48) | RIPK1 | |
| SCHEMBL27971288 | 0.68 | RIPK1 (0.42) | RIPK1KDM1AACHENR1H2NR1H3 | |
| SCHEMBL16543129 | 0.67 | CYP2D6 (0.39) | — | |
| SCHEMBL16543128 | 0.67 | CYP2D6 (0.39) | — | |
| SCHEMBL16543127 | 0.67 | CYP2D6 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105579444-A | Piperidinylindole derivatives and their use as complement factor B inhibitors | NOVARTIS AG | 2016-05-11 | — | — | CN | disclosed |