Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.43 |
| ▸ | CFB | P00751 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28065036 | 0.76 | RIPK1 (0.43) | KDM1ARIPK1 | |
| SCHEMBL28210594 | 0.71 | CFB (0.56) | KDM1ACFBRIPK1CHRNB2CHRNB4 | |
| SCHEMBL16543129 | 0.70 | CYP2D6 (0.39) | — | |
| SCHEMBL16543128 | 0.70 | CYP2D6 (0.39) | — | |
| SCHEMBL16543127 | 0.70 | CYP2D6 (0.39) | — | |
| SCHEMBL28858375 | 0.67 | CFB (0.58) | KDM1ACFBRIPK1CHRNB2CHRNB4 | |
| Hydrochloric Acid SCHEMBL8604291 | 0.67 | KDM1A (0.39) | KDM1ACFB | |
| SCHEMBL10115579 | 0.66 | ALDH1A1 (0.55) | — | |
| SCHEMBL30668566 | 0.64 | SLC6A9 (0.45) | CFBRIPK1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL27131649 | 0.64 | SLC6A9 (0.45) | CFBRIPK1CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105579444-B | Piperidinylindole derivatives and their use as complement factor B inhibitors | 诺华股份有限公司 | 2018-05-01 | — | — | CN | disclosed |