Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.38 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL966044 | 1.00 | CA12 (0.39) | CA12CA1CA2CA4CA9 | |
| SCHEMBL12920472 | 0.87 | PGR (0.39) | CA12CA1CA2CA4CA9 | |
| SCHEMBL25167208 | 0.85 | EPHX1 (0.47) | CA12CA1CA2CA4CA9 | |
| SCHEMBL966639 | 0.85 | EPHX1 (0.47) | CA12CA1CA2CA4CA9 | |
| SCHEMBL963917 | 0.84 | EPHX1 (0.46) | CA12CA1CA2CA4CA9 | |
| SCHEMBL966466 | 0.82 | LMNA (0.41) | CA12CA1CA2CA4CA9 | |
| SCHEMBL16322044 | 0.82 | LMNA (0.41) | CA12CA1CA2CA4CA9 | |
| SCHEMBL28065141 | 0.77 | PTGS2 (0.49) | MLKLLMNACXCR1CXCR2ADRB2 | |
| SCHEMBL12129521 | 0.77 | PTGS2 (0.49) | MLKLLMNACXCR1CXCR2ADRB2 | |
| SCHEMBL30448999 | 0.75 | LMNA (0.40) | CA12CA1CA2CA9MLKL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105722972-A | Cellular factors involved in the cytotoxicity of leukocidins of staphylococcus aureus: novel therapeutic target | 纽约大学 | 2016-06-29 | — | — | CN | disclosed |