Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | TSHR | P16473 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | NPY1R | P25929 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ACP1 | P24666 | 4/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TOP2A | P11388 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13930025 | 0.87 | SMN1; SMN2 (0.58) | ALDH1A1SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL4246664 | 0.86 | SMN1; SMN2 (0.57) | ALDH1A1SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL1326596 | 0.77 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL4242686 | 0.74 | LMNA (0.65) | ALDH1A1SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL1463935 | 0.71 | ALDH1A1 (0.77) | ALDH1A1SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL1085597 | 0.71 | ACP1 (0.87) | ALDH1A1SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL8691758 | 0.71 | CHRM1 (0.63) | ALDH1A1SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL10746799 | 0.71 | ELANE (0.61) | ALDH1A1SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL4957015 | 0.70 | MAPT (0.62) | ALDH1A1SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL30457841 | 0.70 | ACP1 (1.00) | KMT2AMEN1LMNAACP1TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105593224-A | Novel quinazolinones as bromodomain inhibitors | ZENITH EPIGENETICS CORP | 2016-05-18 | — | — | CN | disclosed |