SCHEMBL28065368

SCHEMBL28065368

OC(CCc1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.52
CHRM2 P08172 7/20 0.52
CHRM1 P11229 7/20 0.52
CYP2D6 P10635 4/20 0.52
HTR1A P08908 2/20 0.52
OPRM1 P35372 2/20 0.52
KCNH2 Q12809 2/20 0.52
LMNA P02545 2/20 0.52
CYP2C9 P11712 3/20 0.50
CYP2C19 P33261 3/20 0.50
CYP1A2 P05177 2/20 0.50
CHRM4 P08173 7/20 0.49
CHRM5 P08912 7/20 0.49
CHRM3 P20309 7/20 0.49
SIGMAR1 Q99720 2/20 0.49
KDM4E B2RXH2 1/20 0.49
DRD2 P14416 1/20 0.49
DRD1 P21728 1/20 0.49
HTR2A P28223 1/20 0.49
DRD3 P35462 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28593755 0.89 BCL2 (0.58) SMN1; SMN2CHRM2CHRM1CYP2D6HTR1A
SCHEMBL28598321 0.89 MEN1 (0.59) SMN1; SMN2CHRM2CHRM1CYP2D6HTR1A
SCHEMBL28586068 0.85 ALDH1A1 (0.50) SMN1; SMN2CHRM2CHRM1CYP2D6HTR1A
SCHEMBL28596222 0.84 SMN1; SMN2 (0.55) SMN1; SMN2CHRM2CHRM1KCNH2LMNA
SCHEMBL560935 0.83 SMN1; SMN2 (0.61) SMN1; SMN2CHRM2CHRM1CYP2D6HTR1A
SCHEMBL4779153 0.82 CYP2C9 (0.50) SMN1; SMN2CYP2D6OPRM1LMNACYP2C9
SCHEMBL28508798 0.79 SLC13A5 (0.57) SMN1; SMN2CHRM2CHRM1CYP2D6HTR1A
SCHEMBL26326648 0.78 CYP2C19 (0.47) SMN1; SMN2CYP2C9CYP2C19CYP1A2TDP1
SCHEMBL8375787 0.78 CYP1A2 (0.47) SMN1; SMN2OPRM1LMNACYP2C9CYP2C19
SCHEMBL27491063 0.78 CYP1A2 (0.47) CHRM2CHRM1CYP2D6HTR1AOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115613084-A Cyanide-free alkali copper electroplating solution and use method thereof 江门市优彼思半导体材料有限公司 2023-01-17 CN claimed
CN-115613084-A Cyanide-free alkali copper electroplating solution and use method thereof 江门市优彼思半导体材料有限公司 2023-01-17 CN disclosed
CN-111163761-A Targeted drugs related to trimethylamine and/or trimethylamine-N-oxide 普梭梅根公司 2020-05-15 CN disclosed
CN-104327025-B A kind of preparation method of 4-arylnaphthalene lactone derivative ZHEJIANG UNIVERSITY (CN) 2016-04-13 CN disclosed