Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21382895 | 0.84 | KDM4E (0.53) | KDM4EALDH1A1GAAHPGDKMT2A | |
| SCHEMBL28828233 | 0.79 | KDM4E (0.65) | KDM4EALDH1A1GAAMAPTKMT2A | |
| SCHEMBL384076 | 0.79 | KDM4E (0.61) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL28600927 | 0.76 | NUDT1 (0.43) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL29215313 | 0.72 | KDM4E (0.56) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL225976 | 0.70 | SMN1; SMN2 (0.37) | KDM4EALDH1A1MAPTHPGDLMNA | |
| SCHEMBL31448436 | 0.69 | TDP1 (0.69) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL1450354 | 0.69 | NPC1 (0.53) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL23625965 | 0.68 | SRC (0.51) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL28586210 | 0.68 | ESR1 (0.51) | KDM4EALDH1A1GAAHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105683182-A | Biaryl acetamide compounds and methods of use thereof | 埃姆比特生物科学公司 | 2016-06-15 | — | — | CN | disclosed |