Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21382895 | 0.84 | KDM4E (0.53) | KDM4EPKML3MBTL1TDP1LMNA | |
| SCHEMBL28338278 | 0.81 | KDM4E (0.68) | KDM4EPKML3MBTL1TDP1LMNA | |
| SCHEMBL28065527 | 0.79 | KDM4E (0.47) | KDM4EPKML3MBTL1TDP1LMNA | |
| SCHEMBL1545355 | 0.79 | KDM4E (1.00) | KDM4EPKML3MBTL1TDP1LMNA | |
| SCHEMBL28600927 | 0.76 | NUDT1 (0.43) | KDM4EPKML3MBTL1TDP1LMNA | |
| SCHEMBL19819297 | 0.76 | KDM4E (0.92) | KDM4EPKML3MBTL1TDP1LMNA | |
| SCHEMBL10562765 | 0.72 | KDM4E (0.77) | KDM4EPKML3MBTL1TDP1LMNA | |
| SCHEMBL21941945 | 0.71 | KDM4E (0.75) | KDM4EPKML3MBTL1TDP1LMNA | |
| SCHEMBL30939449 | 0.71 | KDM4E (0.75) | KDM4EPKML3MBTL1TDP1LMNA | |
| SCHEMBL28474575 | 0.71 | KDM4E (0.81) | KDM4EPKML3MBTL1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105683182-A | Biaryl acetamide compounds and methods of use thereof | 埃姆比特生物科学公司 | 2016-06-15 | — | — | CN | disclosed |