SCHEMBL21382895

SCHEMBL21382895

[c]1cccc(-c2nc3ccccc3nc2-c2ccccc2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.53
L3MBTL1 Q9Y468 6/20 0.53
LMNA P02545 4/20 0.53
TDP1 Q9NUW8 3/20 0.53
GAA P10253 3/20 0.53
KMT2A Q03164 2/20 0.53
MEN1 O00255 1/20 0.53
PKM P14618 1/20 0.50
ALDH1A1 P00352 7/20 0.49
NPSR1 Q6W5P4 1/20 0.49
THRB P10828 1/20 0.47
AKT1 P31749 1/20 0.46
AKT2 P31751 1/20 0.46
ATM Q13315 1/20 0.46
TLR9 Q9NR96 1/20 0.46
HPGD P15428 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
PDE10A Q9Y233 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28065527 0.84 KDM4E (0.47) KDM4EL3MBTL1LMNATDP1GAA
SCHEMBL28828233 0.84 KDM4E (0.65) KDM4EL3MBTL1LMNATDP1GAA
SCHEMBL28600927 0.84 NUDT1 (0.43) KDM4EL3MBTL1LMNATDP1GAA
Water SCHEMBL27680271 0.83 KDM4E (0.71) KDM4EL3MBTL1LMNATDP1GAA
SCHEMBL15987437 0.82 KDM4E (0.50) KDM4EL3MBTL1LMNATDP1GAA
SCHEMBL714997 0.82 KDM4E (0.59) KDM4EL3MBTL1LMNATDP1GAA
SCHEMBL732131 0.81 KDM4E (0.74) KDM4EL3MBTL1LMNATDP1GAA
SCHEMBL29382173 0.81 KDM4E (0.74) KDM4EL3MBTL1LMNATDP1GAA
SCHEMBL28710728 0.79 KDM4E (0.71) KDM4EL3MBTL1LMNATDP1GAA
SCHEMBL13950894 0.79 KDM4E (0.78) KDM4EL3MBTL1LMNATDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111683942-A Compound, organic light emitting device and display device SK材料有限公司 2020-09-18 CN disclosed
WO-2019182360-A1 COMPOUND, ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY DEVICE 에스케이머티리얼즈 주식회사 2019-09-26 WO disclosed