Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 3/20 | 0.33 |
| ▸ | ALAD | P13716 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28005777 | 0.86 | DHODH (0.32) | DHODH | |
| SCHEMBL28014013 | 0.85 | MAPK1 (0.35) | ALADMEN1KMT2A | |
| SCHEMBL28853365 | 0.85 | ALPL (0.31) | RXFP1MCL1MEN1GFERKMT2A | |
| SCHEMBL28026523 | 0.85 | BCL2L1 (0.39) | KMT2A | |
| SCHEMBL28841114 | 0.85 | CES2 (0.33) | — | |
| SCHEMBL28099170 | 0.83 | CA1 (0.40) | MEN1KMT2A | |
| SCHEMBL28069748 | 0.82 | CA1 (0.32) | — | |
| SCHEMBL28084024 | 0.81 | MAOB (0.32) | DHODH | |
| SCHEMBL28164688 | 0.80 | CYP3A4 (0.31) | — | |
| SCHEMBL27662744 | 0.77 | KDM4E (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107849053-A | Spiro compounds | 卡利拉制药公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-106632061-A | Synthesis method of 1-(4-phenyl-1-alkyl-1H-imidazol-2-yl)ethanone and derivative thereof | 上海皓元医药股份有限公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-105683183-A | Substituted pyridine-piperazinyl analogues as RSV antiviral compounds | 爱尔兰詹森科学公司 | 2016-06-15 | — | — | CN | disclosed |