Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | BAD | Q92934 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GRK2 | P25098 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | RPA1 | P27694 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28005777 | 0.86 | DHODH (0.32) | CCR2ALDH1A1RARARARBRARG | |
| SCHEMBL28065629 | 0.85 | FPR2 (0.33) | KMT2A | |
| SCHEMBL28853365 | 0.85 | ALPL (0.31) | POLBALPLKMT2A | |
| SCHEMBL28014013 | 0.85 | MAPK1 (0.35) | CCR2PTGS1PTGS2POLBKMT2A | |
| SCHEMBL28069748 | 0.82 | CA1 (0.32) | — | |
| SCHEMBL28841114 | 0.82 | CES2 (0.33) | — | |
| SCHEMBL28164688 | 0.80 | CYP3A4 (0.31) | CYP3A4 | |
| SCHEMBL28049312 | 0.79 | RXRA (0.34) | — | |
| SCHEMBL28138029 | 0.77 | CA1 (0.37) | POLBHCAR3HCAR2GPR35 | |
| SCHEMBL27332909 | 0.76 | HPGDS (0.38) | CYP3A4CYP2C9HCAR2CA12RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104837844-B | Pyrazole substituted imidazopiperazines as casein kinase 1D/E inhibitors | 百时美施贵宝公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-104837844-A | Pyrazole substituted imidazopiperazines as casein kinase 1D/E inhibitors | BRISTOL MYERS SQUIBB CO | 2015-08-12 | — | — | CN | disclosed |