Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3293181 | 0.80 | ALDH1A1 (0.50) | CASP6NR4A2MAPTMEN1KMT2A | |
| SCHEMBL30903381 | 0.80 | CASP6 (0.52) | CASP6NR4A2MAPTMEN1KMT2A | |
| SCHEMBL24971013 | 0.80 | CASP6 (0.52) | CASP6NR4A2MAPTMEN1KMT2A | |
| SCHEMBL29987120 | 0.77 | CASP6 (0.58) | CASP6NR4A2MAPTMEN1KMT2A | |
| SCHEMBL28065783 | 0.77 | TDP1 (0.46) | CASP6NR4A2MAPTMEN1KMT2A | |
| SCHEMBL28107525 | 0.77 | TDP1 (0.46) | CASP6NR4A2MAPTMEN1KMT2A | |
| SCHEMBL846680 | 0.74 | KMT2A (0.55) | CASP6MAPTMEN1KMT2ANPC1 | |
| SCHEMBL28753586 | 0.73 | CASP6 (0.86) | CASP6NR4A2MAPTMEN1KMT2A | |
| SCHEMBL1993651 | 0.73 | TOP1 (0.50) | NR4A2NPC1POLBL3MBTL1TDP1 | |
| SCHEMBL27963113 | 0.73 | NPSR1 (0.43) | CASP6NR4A2MAPTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118724895-A | Condensed ring amine derivative inhibitor, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-102007125-B | fused heterocyclic derivatives and methods of use | AMGEN INC. (US) | 2016-05-25 | — | — | CN | disclosed |