Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 known ✓ | P41143 | 7/20 | 0.35 |
| ▸ | SLC6A2 known ✓ | P23975 | 3/20 | 0.33 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.33 |
| ▸ | OPRM1 known ✓ | P35372 | 3/20 | 0.32 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3533330 | 0.90 | OPRD1 (0.36) | OPRD1SLC6A2SIGMAR1SLC6A4CHRM5 | |
| SCHEMBL431808 | 0.90 | OPRD1 (0.36) | OPRD1SLC6A2SIGMAR1SLC6A4CHRM5 | |
| Hydrochloric Acid SCHEMBL6956721 | 0.88 | SMN1; SMN2 (0.38) | OPRD1SLC6A2SIGMAR1SLC6A4CYP3A4 | |
| Sulfuric Acid SCHEMBL28081787 | 0.86 | TP53 (0.30) | — | |
| SCHEMBL11543878 | 0.82 | OPRD1 (0.38) | OPRD1SLC6A2SIGMAR1SLC6A4CHRM2 | |
| SCHEMBL28904186 | 0.79 | CXCR4 (0.40) | OPRD1SLC6A2SIGMAR1SLC6A4CHRM2 | |
| Sulfuric Acid SCHEMBL29036121 | 0.79 | OPRD1 (0.35) | OPRD1SLC6A2SIGMAR1SLC6A4LMNA | |
| Allyl Alcohol SCHEMBL11188821 | 0.78 | TSHR (0.32) | OPRD1TSHR | |
| SCHEMBL11184153 | 0.78 | ALDH1A1 (0.32) | OPRD1 | |
| SCHEMBL22711078 | 0.78 | OPRM1 (0.34) | OPRD1SLC6A2SIGMAR1SLC6A4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105498504-A | Iron ore agglomeration sintering tail gas purifying device and purifying method as well as application thereof | TONGGUAN SMELTING BRANCH OF TONGLING NONFERROUS METALS GROUP CO LTD | 2016-04-20 | — | — | CN | disclosed |