SCHEMBL2806690

SCHEMBL2806690

COC(=O)C#C[Au][PH](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.40
KMT2A Q03164 6/20 0.36
MAPT P10636 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
MEN1 O00255 3/20 0.34
HPGD P15428 2/20 0.34
CES1 P23141 2/20 0.34
MAPK1 P28482 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP3A4 P08684 1/20 0.34
ALOX15 P16050 1/20 0.34
NPC1 O15118 4/20 0.34
SRC P12931 1/20 0.34
RAB9A P51151 4/20 0.33
POLB P06746 2/20 0.33
KCNN4 O15554 1/20 0.33
CASP3 P42574 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL737243 0.70 MAPT (0.43) MAPTSMN1; SMN2HPGDNPC1RAB9A
SCHEMBL3198121 0.69 TSHR (0.52) TSHRKMT2AMAPTSMN1; SMN2MEN1
SCHEMBL738373 0.68 ALDH1A1 (0.44) TSHRKMT2AMAPTSMN1; SMN2MEN1
SCHEMBL124863 0.67 NPSR1 (0.55) TSHRKMT2AMEN1KDM4ENPC1
SCHEMBL1636983 0.67 ACACB (0.41) KMT2AMAPTSMN1; SMN2MEN1HPGD
SCHEMBL1635668 0.66 AKR1C3 (0.42) KMT2AMAPTSMN1; SMN2MEN1TDP1
SCHEMBL2805373 0.66
SCHEMBL736791 0.66 APP (0.43) KMT2AMEN1CES1TDP1NPC1
SCHEMBL738590 0.65 APP (0.46) TSHRKMT2AMAPTSMN1; SMN2MEN1
SCHEMBL8975628 0.65 TSHR (0.45) TSHRKMT2AMAPTSMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100237770-A1 GOLD COMPLEX AND PROCESS FOR PREPARING THE SAME, AND ORGANIC ULTRAVIOLET ELECTROLUMINESCENT DEVICE USING SAID GOLD COMPLEX UBE INDUSTRIES, LTD. (JP) 2010-09-23 US disclosed
EP-2088151-A1 GOLD COMPLEX, METHOD FOR PRODUCTION OF THE GOLD COMPLEX, AND ORGANIC ULTRAVIOLET ELECTROLUMINESCENT ELEMENT USING THE GOLD COMPLEX Ube Industries, Ltd. (JP) 2009-08-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100237770-A1 GOLD COMPLEX AND PROCESS FOR PREPARING THE SAME, AND ORGANIC ULTRAVIOLET ELECTROLUMINESCENT DEVICE USING SAID GOLD COMPLEX APOL1, UFL1, ACSL3 TSHR 2791/4885KMT2A 2970/4885MAPT 3415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.