Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 known ✓ | P25103 | 6/20 | 0.51 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.44 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.43 |
| ▸ | SCN4A | P35499 | 2/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30994721 | 0.97 | TACR1 (0.53) | TACR1SCN4AMCHR1CHRM2CHRM4 | |
| SCHEMBL1339973 | 0.97 | TACR1 (0.53) | TACR1SCN4AMCHR1CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL719130 | 0.96 | TACR1 (0.54) | TACR1SCN4AMCHR1CHRM2CHRM4 | |
| SCHEMBL26703594 | 0.86 | S1PR1 (0.45) | TACR1BCHEACHE | |
| SCHEMBL2239996 | 0.86 | TACR1 (0.48) | TACR1 | |
| SCHEMBL2237347 | 0.86 | ALDH1A1 (0.49) | SIGMAR1 | |
| SCHEMBL22634122 | 0.85 | OPRM1 (0.44) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL159259 | 0.85 | L3MBTL1 (0.54) | TACR1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL8126942 | 0.84 | CHRM2 (0.47) | MCHR1CHRM2CHRM4CHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL1000168 | 0.84 | L3MBTL1 (0.53) | TACR1CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105925200-A | Silicone sealant for automotive chassis | 烟台图文马克化工科技有限公司 | 2016-09-07 | — | — | CN | disclosed |