Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isophthalic Acid SCHEMBL28068125 | 0.99 | MAPT (0.38) | MAPTCYP1A2CYP2C9KMT2AMEN1 | |
| SCHEMBL16626787 | 0.81 | HTR6 (0.40) | MAPTCYP1A2CYP2C9KMT2AMEN1 | |
| Isophthalic Acid SCHEMBL28068084 | 0.80 | HTR6 (0.45) | MAPT | |
| Hydrochloric Acid SCHEMBL16618771 | 0.80 | HTR6 (0.39) | MAPTCYP1A2CYP2C9KMT2AMEN1 | |
| Isophthalic Acid SCHEMBL28068139 | 0.77 | KMO (0.42) | MAPTKMT2APOLB | |
| Isophthalic Acid SCHEMBL28068050 | 0.76 | KMO (0.41) | MAPTKMT2APOLB | |
| Isophthalic Acid SCHEMBL28068089 | 0.76 | AKR1C3 (0.40) | MAPTLMNAPPARGAKR1C3ALDH1A1 | |
| Isophthalic Acid SCHEMBL28068093 | 0.76 | LMNA (0.39) | LMNAPPARGAKR1C3 | |
| Isophthalic Acid SCHEMBL28068086 | 0.75 | AKR1C3 (0.39) | MAPTLMNAPPARGAKR1C3ALDH1A1 | |
| Isophthalic Acid SCHEMBL28068081 | 0.73 | CKS1B (0.38) | KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | claimed |