Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.45 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isophthalic Acid SCHEMBL28068139 | 0.93 | KMO (0.42) | HTR6KMOACLYCSNK2A2CSNK2B | |
| Isophthalic Acid SCHEMBL28068050 | 0.92 | KMO (0.41) | HTR6KMOACLYCSNK2A2CSNK2B | |
| Isophthalic Acid SCHEMBL28068081 | 0.85 | CKS1B (0.38) | HTR6KMOPTGS2 | |
| Isophthalic Acid SCHEMBL28068089 | 0.84 | AKR1C3 (0.40) | HTR6PTGS2MAPT | |
| Isophthalic Acid SCHEMBL28068086 | 0.84 | AKR1C3 (0.39) | HTR6PTGS2MAPT | |
| Isophthalic Acid SCHEMBL28068046 | 0.80 | MAPT (0.39) | MAPT | |
| Isophthalic Acid SCHEMBL28068125 | 0.80 | MAPT (0.38) | MAPT | |
| Isophthalic Acid SCHEMBL28068093 | 0.79 | LMNA (0.39) | CYP11B1CYP11B2 | |
| SCHEMBL16619172 | 0.77 | HTR6 (0.46) | HTR6 | |
| SCHEMBL16619000 | 0.77 | HTR6 (0.46) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | claimed |
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | disclosed |