Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 8/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.42 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30859041 | 0.78 | CA1 (0.65) | AKR1B1CA1CA2MMP1MMP2 | |
| SCHEMBL8863056 | 0.78 | CA1 (0.65) | AKR1B1CA1CA2MMP1MMP2 | |
| SCHEMBL6954043 | 0.76 | HSD17B10 (0.42) | CA12CA9 | |
| Hydrochloric Acid SCHEMBL11261755 | 0.76 | CA1 (0.62) | AKR1B1CA1CA2MMP1MMP2 | |
| SCHEMBL28068079 | 0.76 | HTR6 (0.41) | HTR6 | |
| SCHEMBL28207032 | 0.76 | ESR1 (0.54) | AKR1B1CA1CA2MMP1MMP2 | |
| SCHEMBL20758153 | 0.75 | CA1 (0.57) | AKR1B1CA1CA2MMP1MMP2 | |
| SCHEMBL7697167 | 0.73 | CA1 (0.59) | AKR1B1CA1CA2MMP1MMP2 | |
| SCHEMBL15535303 | 0.72 | CA1 (0.54) | AKR1B1CA1CA2MMP1MMP2 | |
| SCHEMBL4537377 | 0.72 | NAMPT (0.50) | AKR1B1CA1CA2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612150-B | Sulfonylindole derivatives and process for producing the same | 株式会社大熊制药 | 2018-04-10 | — | — | CN | disclosed |
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | disclosed |