Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.41 |
| ▸ | FBP1 | P09467 | 2/20 | 0.35 |
| ▸ | DUT | P33316 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28068077 | 0.76 | AKR1B1 (0.45) | HTR6 | |
| SCHEMBL22954631 | 0.75 | HTR6 (0.48) | HTR6FBP1KDM2BDRD1HDAC3 | |
| SCHEMBL5435375 | 0.70 | ALOX15 (0.34) | KMT2AATMDRD1DAO | |
| SCHEMBL14572837 | 0.68 | KDM2B (0.48) | HTR6FBP1DUTKDM2BDRD1 | |
| SCHEMBL12310498 | 0.68 | CA2 (0.55) | FBP1DRD1 | |
| SCHEMBL113409 | 0.68 | DRD1 (0.44) | HTR6FBP1KMT2AKDM2BDRD1 | |
| SCHEMBL21233207 | 0.68 | PDE4A (0.46) | HTR6FBP1KDM2BDRD1BRD4 | |
| SCHEMBL1134333 | 0.68 | TSHR (0.47) | HTR6FBP1KMT2AATMKDM2B | |
| SCHEMBL617654 | 0.66 | HTR6 (0.66) | HTR6 | |
| SCHEMBL22952851 | 0.66 | NR1H2 (0.43) | HTR6FBP1KDM2BDRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612150-B | Sulfonylindole derivatives and process for producing the same | 株式会社大熊制药 | 2018-04-10 | — | — | CN | disclosed |
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | disclosed |