Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 10/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR1E | P28566 | 1/20 | 0.36 |
| ▸ | HTR1F | P30939 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28068112 | 0.84 | HTR6 (0.46) | HTR6CHRNB4CHRNA3CYP11B1CYP11B2 | |
| SCHEMBL28068045 | 0.83 | HTR6 (0.42) | HTR6CHRNB4CHRNA3PPARGPPARD | |
| Hydrochloric Acid SCHEMBL28068041 | 0.83 | HTR6 (0.45) | HTR6CHRNB4CHRNA3CYP11B1CYP11B2 | |
| SCHEMBL28068087 | 0.81 | KMT2A (0.49) | HTR6CHRNB4CHRNA3CYP11B1CYP11B2 | |
| SCHEMBL17971581 | 0.75 | HTR6 (0.44) | HTR6CYP2C9LMNAHTR1ADRD2 | |
| SCHEMBL19971359 | 0.75 | HTR6 (0.42) | HTR6CHRNB4CHRNA3PPARGPPARD | |
| SCHEMBL16626785 | 0.74 | HTR6 (0.44) | HTR6CYP11B1CYP11B2HTR1ADRD2 | |
| SCHEMBL16626404 | 0.74 | HTR6 (0.45) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL28829305 | 0.74 | HTR6 (0.43) | HTR6CHRNB4CHRNA3CYP2C9KEAP1 | |
| SCHEMBL16626784 | 0.74 | HTR6 (0.42) | HTR6PPARGPPARDPPARACYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | disclosed |