Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16618555 | 0.88 | KMT2A (0.52) | KMT2AMEN1CHRNB4CHRNA3PIK3CG | |
| SCHEMBL28068112 | 0.84 | HTR6 (0.46) | CHRNB4CHRNA3KEAP1NFE2L2HTR6 | |
| SCHEMBL28068045 | 0.84 | HTR6 (0.42) | KMT2ACHRNB4CHRNA3MMP1MMP9 | |
| Hydrochloric Acid SCHEMBL28068041 | 0.84 | HTR6 (0.45) | CHRNB4CHRNA3KEAP1NFE2L2HTR6 | |
| SCHEMBL16618849 | 0.82 | KMT2A (0.56) | KMT2AMEN1PIK3CGHDAC1HDAC2 | |
| SCHEMBL28068091 | 0.81 | HTR6 (0.42) | CHRNB4CHRNA3LMNAKEAP1NFE2L2 | |
| SCHEMBL28207078 | 0.80 | KMT2A (0.76) | KMT2AMEN1LMNANR4A2KDM4E | |
| SCHEMBL19971462 | 0.79 | LMNA (0.43) | KMT2AMEN1CHRNB4CHRNA3PIK3CG | |
| SCHEMBL16619065 | 0.78 | NR4A2 (0.49) | KMT2AMEN1PIK3CGNR4A2CYP11B1 | |
| SCHEMBL16618580 | 0.77 | NR4A2 (0.50) | KMT2AMEN1LMNANR4A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612150-B | Sulfonylindole derivatives and process for producing the same | 株式会社大熊制药 | 2018-04-10 | — | — | CN | claimed |
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | claimed |
| CN-105612150-B | Sulfonylindole derivatives and process for producing the same | 株式会社大熊制药 | 2018-04-10 | — | — | CN | disclosed |
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | disclosed |