SCHEMBL28068268

SCHEMBL28068268

O=C(O)c1ccc(Oc2cncc(C(=O)O)c2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP15 Q460N3 1/20 0.55
PARP10 Q53GL7 1/20 0.55
SRD5A2 P31213 4/20 0.53
SIRT2 Q8IXJ6 1/20 0.51
SIRT1 Q96EB6 1/20 0.51
SIRT3 Q9NTG7 1/20 0.51
RXRA P19793 1/20 0.50
RXRB P28702 1/20 0.50
RXRG P48443 1/20 0.50
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
HTT P42858 1/20 0.49
GFER P55789 1/20 0.49
HSD17B10 Q99714 1/20 0.49
AKR1C3 P42330 1/20 0.49
HCAR2 Q8TDS4 4/20 0.47
POLB P06746 2/20 0.47
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
LMNA P02545 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1202826 0.89 AKR1C3 (0.62) PARP10SRD5A2SIRT2SIRT1SIRT3
SCHEMBL2427437 0.88 XDH (0.58) SIRT2SIRT1SIRT3MEN1KMT2A
SCHEMBL7425499 0.85 HCAR2 (0.56) PARP15PARP10SRD5A2HCAR2
SCHEMBL29702964 0.83 POLB (0.55) SIRT2SIRT1SIRT3MEN1KMT2A
SCHEMBL6014080 0.83 MEN1 (0.71) SRD5A2MEN1KMT2APOLBKDM4E
SCHEMBL2193673 0.81 ALDH1A1 (0.58) SIRT2SIRT1SIRT3MEN1KMT2A
SCHEMBL15314411 0.81 HCAR2 (0.53) PARP15PARP10SIRT2SIRT1SIRT3
Terephthalic Acid SCHEMBL9861713 0.80 PARP10 (0.78) PARP15PARP10SRD5A2RXRARXRB
SCHEMBL22281 0.80 PARP10 (0.78) PARP15PARP10SRD5A2RXRARXRB
SCHEMBL766069 0.80 PARP10 (0.78) PARP15PARP10SRD5A2RXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112044459-B Punicallyid porous nickel-based phosphide nano-structure material and preparation method and application thereof 中山大学 2022-02-18 CN claimed
CN-105541885-A Niacin derivative ligand samarium metal complex with light-emitting function and preparation method thereof UNIV NANYANG NORMAL 2016-05-04 CN claimed
CN-112044459-B Punicallyid porous nickel-based phosphide nano-structure material and preparation method and application thereof 中山大学 2022-02-18 CN disclosed
CN-105541885-A Niacin derivative ligand samarium metal complex with light-emitting function and preparation method thereof UNIV NANYANG NORMAL 2016-05-04 CN disclosed
CN-105541885-A Niacin derivative ligand samarium metal complex with light-emitting function and preparation method thereof UNIV NANYANG NORMAL 2016-05-04 CN disclosed