Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.51 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28068268 | 0.85 | PARP15 (0.55) | HCAR2PARP15PARP10SRD5A2 | |
| SCHEMBL7429971 | 0.83 | ALDH1A1 (0.52) | — | |
| SCHEMBL11545406 | 0.79 | LTA4H (0.48) | XDHSLC22A12 | |
| SCHEMBL10236868 | 0.79 | RXRA (0.66) | HCAR2 | |
| SCHEMBL1995706 | 0.79 | TSHR (0.74) | PARP15PARP10SRD5A2 | |
| SCHEMBL28347124 | 0.78 | MAP4K4 (0.49) | PTGER4XDHSLC22A12 | |
| SCHEMBL28347123 | 0.78 | MAP4K4 (0.49) | PTGER4XDHSLC22A12 | |
| SCHEMBL30335327 | 0.78 | MAP4K4 (0.49) | PTGER4XDHSLC22A12 | |
| SCHEMBL15011761 | 0.77 | RXRA (0.63) | PTGER4PARP15PARP10SRD5A2 | |
| SCHEMBL30982340 | 0.77 | RXRA (0.63) | PTGER4PARP15PARP10SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000048993-A1 | ARYLAMINOALKYLAMIDES | NOVARTIS AG (CH) | 2000-08-24 | — | — | WO | disclosed |