Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9733231 | 0.95 | ACHE (0.39) | ACHETSHRESR1ALDH1A1CA1 | |
| Hydrochloric Acid SCHEMBL1955171 | 0.85 | TSHR (0.47) | ACHETSHRESR1ALDH1A1CA1 | |
| Iodide SCHEMBL9067572 | 0.80 | TSHR (0.47) | ACHETSHRESR1ALDH1A1CA1 | |
| Bromide SCHEMBL9067697 | 0.80 | TSHR (0.47) | ACHETSHRESR1ALDH1A1CA1 | |
| Bromide SCHEMBL7741553 | 0.79 | GAA (0.36) | ACHETSHRALDH1A1LMNACYP3A4 | |
| Hydrochloric Acid SCHEMBL114803 | 0.77 | HIF1A (0.43) | ACHETSHRALDH1A1HIF1ALMNA | |
| Benzene SCHEMBL27680989 | 0.77 | HIF1A (0.43) | ACHETSHRALDH1A1HIF1ALMNA | |
| SCHEMBL25797536 | 0.76 | ACHE (0.38) | ACHETSHRESR1ALDH1A1CA1 | |
| Hydrochloric Acid SCHEMBL28409965 | 0.75 | TSHR (0.47) | ACHETSHRESR1ALDH1A1CA1 | |
| Hydrochloric Acid SCHEMBL29105928 | 0.75 | HIF1A (0.41) | ACHETSHRALDH1A1HIF1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105746148-A | Early maturing culture method for Tai lake water shield | 苏州东山农业发展有限公司 | 2016-07-13 | — | — | CN | claimed |
| CN-108569724-A | A kind of method of moss in removal water body | 上海太和水环境科技发展股份有限公司 | 2018-09-25 | — | — | CN | disclosed |
| CN-108094442-A | A kind of preparation method of moss removing agent | 仇颖超 | 2018-06-01 | — | — | CN | disclosed |
| CN-106879628-A | A kind of method for removing moss in water | 广州通穗环保科技有限公司 | 2017-06-23 | — | — | CN | disclosed |
| CN-106315869-A | Moss ecological control agent for aquaculture and application thereof | 中国水产科学研究院淡水渔业研究中心 | 2017-01-11 | — | — | CN | disclosed |
| CN-105746148-A | Early maturing culture method for Tai lake water shield | 苏州东山农业发展有限公司 | 2016-07-13 | — | — | CN | disclosed |