Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9067697 | 0.94 | TSHR (0.47) | TSHRACHEALDH1A1CA1CA2 | |
| Hydrochloric Acid SCHEMBL1955171 | 0.94 | TSHR (0.47) | TSHRACHEALDH1A1CA1CA2 | |
| Phosphoric Acid SCHEMBL9067665 | 0.84 | TSHR (0.38) | TSHRACHEALDH1A1CA1CA2 | |
| Acetic Acid SCHEMBL9068177 | 0.82 | ALDH1A1 (0.39) | TSHRACHEALDH1A1CA1TDP1 | |
| Bromide SCHEMBL9733231 | 0.80 | ACHE (0.39) | TSHRACHEALDH1A1CA1CA2 | |
| Hydrochloric Acid SCHEMBL28409965 | 0.78 | TSHR (0.47) | TSHRACHEALDH1A1CA1CA2 | |
| Bromide SCHEMBL28417962 | 0.78 | TSHR (0.47) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL30634705 | 0.77 | TSHR (0.53) | TSHRACHEALDH1A1CA1CA2 | |
| Water SCHEMBL4384424 | 0.74 | TSHR (0.50) | TSHRACHEALDH1A1CA1CA2 | |
| Fluoride Ion SCHEMBL943596 | 0.74 | TSHR (0.50) | TSHRACHEALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534565-A | DICYANDIAMIDE DERIVATIVES FOR LAMINATES | ALLIEDSIGNAL INC. (US) | 1996-07-09 | — | — | US | disclosed |
| WO-1994014866-A1 | SOLVENT FREE EPOXY RESIN COMPOSITIONS | ALLIEDSIGNAL, INC. (US) | 1994-07-07 | — | — | WO | disclosed |