Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27907449 | 0.84 | L3MBTL1 (0.53) | KMT2AMAPTALDH1A1MEN1POLB | |
| SCHEMBL27907456 | 0.83 | KMT2A (0.56) | LMNACYP1A2SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL6222897 | 0.80 | KMT2A (0.82) | LMNACYP1A2SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL31359582 | 0.78 | TDP1 (0.58) | LMNACYP1A2TDP1KMT2AMAPT | |
| SCHEMBL698001 | 0.78 | CA1 (0.58) | CYP1A2KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL7229213 | 0.78 | MAPT (0.63) | LMNACYP1A2SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL7229777 | 0.76 | MAPT (0.64) | LMNACYP1A2SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL28034404 | 0.76 | LMNA (1.00) | LMNACYP1A2SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL11266531 | 0.76 | CES2 (0.57) | LMNACYP1A2TDP1KMT2AMAPT | |
| SCHEMBL11815884 | 0.76 | CES2 (0.76) | LMNACYP1A2SMN1; SMN2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105685064-A | HERBICIDAL ISOXAZOLO[5,4-b]PYRIDINES | 巴斯夫欧洲公司 | 2016-06-22 | — | — | CN | claimed |
| CN-105685064-A | HERBICIDAL ISOXAZOLO[5,4-b]PYRIDINES | 巴斯夫欧洲公司 | 2016-06-22 | — | — | CN | disclosed |