Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | GRM8 | O00222 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30705384 | 0.88 | CHRM1 (0.51) | ALDH1A1HTTLMNACHRM1KCNH2 | |
| SCHEMBL28030353 | 0.79 | LMNA (0.45) | ALDH1A1SMN1; SMN2HTTLMNAGRM8 | |
| SCHEMBL12486019 | 0.78 | CHRNB2 (0.50) | SMN1; SMN2CHRNB2CHRNA4KCNA5KCNN4 | |
| SCHEMBL15385473 | 0.78 | CHRNB2 (0.50) | SMN1; SMN2CHRNB2CHRNA4KCNA5KCNN4 | |
| SCHEMBL27956701 | 0.77 | F7 (0.46) | ALDH1A1SMN1; SMN2HTTLMNAGRM8 | |
| SCHEMBL29931638 | 0.76 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2HTTRAB9ALMNA | |
| SCHEMBL2436131 | 0.76 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2HTTRAB9ALMNA | |
| SCHEMBL30771243 | 0.76 | CHRM1 (0.55) | ALDH1A1HTTLMNACHRM1KCNH2 | |
| SCHEMBL3220273 | 0.75 | KCNA5 (0.50) | ALDH1A1LMNAKCNA5KCNN4FAAH | |
| SCHEMBL28085892 | 0.75 | TBXAS1 (0.49) | SMN1; SMN2LMNAGRM8GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103687860-B | As P2X7Heterocyclic amide derivatives of receptor antagonists | 埃科特莱茵药品有限公司 | 2016-06-08 | — | — | CN | claimed |