Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10941871 | 0.83 | PTGDR2 (0.34) | PTGDR2AKR1C3AKR1C1HTTCYP2D6 | |
| SCHEMBL28068627 | 0.80 | TSHR (0.39) | ADRA2AADRA2BADRA2CGBA1MEN1 | |
| SCHEMBL21784784 | 0.79 | MMP2 (0.42) | PTGDR2ADRA2AADRA2BADRA2CGBA1 | |
| SCHEMBL14661272 | 0.78 | PTGDR2 (0.47) | PTGDR2 | |
| Ammonia Solution, Strong SCHEMBL28615660 | 0.75 | ADRA2A (0.40) | ADRA2AADRA2BADRA2CGBA1TSHR | |
| SCHEMBL415803 | 0.74 | PTGDR2 (0.45) | PTGDR2ADRA2AKMT2ACYP1A2CYP2C9 | |
| SCHEMBL2062948 | 0.74 | PTGDR2 (0.45) | PTGDR2ADRA2AKMT2ACYP1A2CYP2C9 | |
| SCHEMBL418663 | 0.74 | PTGDR2 (0.45) | PTGDR2ADRA2AKMT2ACYP1A2CYP2C9 | |
| SCHEMBL198311 | 0.72 | PTGDR2 (0.48) | PTGDR2MEN1KMT2A | |
| SCHEMBL198081 | 0.72 | PTGDR2 (0.48) | PTGDR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103687860-B | As P2X7Heterocyclic amide derivatives of receptor antagonists | 埃科特莱茵药品有限公司 | 2016-06-08 | — | — | CN | disclosed |