Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 5/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | MGAM | O43451 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | SI | P14410 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GRK6 | P43250 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5351976 | 0.76 | MET (1.00) | METGAAMCL1KDM4EALDH1A1 | |
| SCHEMBL2122340 | 0.75 | HSD17B3 (0.58) | GAAMCL1KDM4EALDH1A1MAPT | |
| 4-Methyldaphnetin SCHEMBL29671915 | 0.74 | MCL1 (1.00) | METGAAMCL1KDM4EALDH1A1 | |
| 4-Methyldaphnetin SCHEMBL1065373 | 0.74 | MCL1 (1.00) | METGAAMCL1KDM4EALDH1A1 | |
| SCHEMBL6616494 | 0.74 | TERT (0.72) | KDM4EALDH1A1MAPTALOX15TP53 | |
| SCHEMBL2417272 | 0.74 | KDM4E (0.59) | GAAMCL1KDM4EALDH1A1MAPT | |
| SCHEMBL14879766 | 0.73 | MET (0.59) | METGAAMCL1KDM4EALDH1A1 | |
| SCHEMBL29749623 | 0.72 | MAOA (0.72) | GAAMCL1KDM4EALDH1A1MAPT | |
| SCHEMBL14898335 | 0.72 | MCL1 (0.77) | METGAAMCL1KDM4EALDH1A1 | |
| SCHEMBL14880010 | 0.72 | MET (0.67) | METGAAMCL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105624268-A | Method for quantitative determination of catechol-o-methyl transferase activity and use thereof | DALIAN INST CHEMICAL PHYSICS CAS | 2016-06-01 | — | — | CN | disclosed |