Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 6/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 6/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28345381 | 0.83 | ACE (0.47) | ACETSHRPDK1PDK2PDK3 | |
| SCHEMBL20462833 | 0.81 | TSHR (0.62) | ACETSHRPDK1PDK2PDK3 | |
| SCHEMBL29746320 | 0.80 | PDK1 (0.48) | ACETSHRPDK1PDK2PDK3 | |
| SCHEMBL3441713 | 0.79 | ACE (0.47) | ACE | |
| SCHEMBL1650576 | 0.78 | PDK1 (0.62) | ACETSHRPDK1PDK2PDK3 | |
| SCHEMBL8018491 | 0.78 | MTNR1A (0.51) | ACETSHRPDK1PDK2PDK3 | |
| SCHEMBL16553514 | 0.77 | BCHE (0.43) | ACETSHRPDK1PDK2PDK3 | |
| SCHEMBL1243267 | 0.75 | HTR2C (0.44) | ACETSHRPDK1PDK2PDK3 | |
| SCHEMBL23505301 | 0.73 | MTNR1A (0.49) | TSHRGAASMN1; SMN2ALDH1A1NOTUM | |
| SCHEMBL9685608 | 0.73 | TSHR (0.41) | TSHRGAASMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105555768-A | ROR gamma modulators | BRISTOL MYERS SQUIBB CO | 2016-05-04 | — | — | CN | disclosed |