SCHEMBL28069049

SCHEMBL28069049

O=CC=NOC(=O)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PLA2G7 Q13093 6/20 0.65
MIF P14174 1/20 0.56
F2 P00734 1/20 0.48
LMNA P02545 1/20 0.48
TSHR P16473 2/20 0.46
TP53 P04637 1/20 0.46
NPC1 O15118 5/20 0.44
RAB9A P51151 5/20 0.44
PKM P14618 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
MAPT P10636 2/20 0.44
TDP1 Q9NUW8 2/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPK1 P28482 1/20 0.42
CDK5 Q00535 3/20 0.41
CDK5R1 Q15078 3/20 0.41
MITF O75030 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL734681 0.80 PLA2G7 (0.67) PLA2G7MIFF2LMNATSHR
SCHEMBL734682 0.80 PLA2G7 (0.67) PLA2G7MIFF2LMNATSHR
SCHEMBL3233878 0.79 PLA2G7 (1.00) PLA2G7MIFLMNANPC1RAB9A
SCHEMBL3233883 0.79 PLA2G7 (1.00) PLA2G7MIFLMNANPC1RAB9A
SCHEMBL13431306 0.79 PLA2G7 (1.00) PLA2G7MIFLMNANPC1RAB9A
SCHEMBL2532511 0.78 PLA2G7 (0.65) PLA2G7MIFF2LMNATSHR
SCHEMBL2890648 0.78 PLA2G7 (0.65) PLA2G7MIFF2LMNATSHR
SCHEMBL10406729 0.78 PLA2G7 (0.65) PLA2G7MIFF2LMNATSHR
SCHEMBL3222751 0.77 PLA2G7 (1.00) PLA2G7MIFF2LMNANPC1
SCHEMBL3222745 0.77 PLA2G7 (1.00) PLA2G7MIFF2LMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105765458-A Negative photosensitive resin composition 日产化学工业株式会社 2016-07-13 CN disclosed