SCHEMBL28249286

SCHEMBL28249286

CC(C)(CO)c1cc(-c2ccccc2)c(O)c(C(C)(C)CO)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.42
CNR2 P34972 1/20 0.42
BACE1 P56817 2/20 0.41
PDE4B Q07343 3/20 0.40
HDAC4 P56524 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
PTPN1 P18031 3/20 0.36
PDE4A P27815 2/20 0.36
PDE4C Q08493 2/20 0.36
PDE4D Q08499 2/20 0.36
PTPN2 P17706 1/20 0.36
PTPN6 P29350 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
TSHR P16473 1/20 0.36
CYP2C19 P33261 1/20 0.36
PTPN5 P54829 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28069366 0.86 MAPK1 (0.43) BACE1PDE4BHDAC4HDAC2HDAC8
SCHEMBL10495879 0.80 ALDH1A1 (0.42) CNR1CNR2CYP1A2CYP3A4CYP2C9
SCHEMBL6320034 0.78 CYP1A2 (0.53) BACE1PTPN1CYP1A2CYP3A4CYP2C9
SCHEMBL2596765 0.78 SHBG (0.39) BACE1CYP3A4PTPN5
SCHEMBL2995994 0.77 CYP3A4 (0.44) CNR1CNR2BACE1PTPN1CYP1A2
SCHEMBL199860 0.77 SHBG (0.47) BACE1PDE4BHDAC4HDAC2HDAC8
SCHEMBL14820672 0.75 CYP1A2 (0.50) BACE1PTPN1CYP1A2CYP3A4CYP2C9
SCHEMBL5706284 0.75 CNR1 (0.48) CNR1CNR2BACE1PDE4BPTPN1
SCHEMBL200188 0.73 BACE1 (0.49) BACE1PDE4BHDAC4HDAC2HDAC8
SCHEMBL296464 0.73 BACE1 (0.49) CNR1CNR2BACE1PDE4BHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106009182-B A kind of high-strength nuclear power polyvinyl piping materials 上海中塑管业有限公司 2018-10-30 CN disclosed