Acetamide

Acetamide

SCHEMBL28069463

CC(N)=O.O=C(c1ccccc1)c1cc(Cl)ccc1Cl

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
MAPT P10636 2/20 0.56
LMNA P02545 2/20 0.56
S100B P04271 1/20 0.55
RAB9A P51151 1/20 0.54
GABRP O00591 1/20 0.53
GABRD O14764 1/20 0.53
GABRA1 P14867 1/20 0.53
GABRB1 P18505 1/20 0.53
GABRG2 P18507 1/20 0.53
GABRB3 P28472 1/20 0.53
GABRA5 P31644 1/20 0.53
GABRA3 P34903 1/20 0.53
GABRA2 P47869 1/20 0.53
GABRB2 P47870 1/20 0.53
GABRA4 P48169 1/20 0.53
GABRE P78334 1/20 0.53
GABRA6 Q16445 1/20 0.53
GABRG1 Q8N1C3 1/20 0.53
GABRG3 Q99928 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29612638 0.92 ALDH1A1 (0.63) ALDH1A1MAPTLMNAS100BRAB9A
SCHEMBL230930 0.92 ALDH1A1 (0.63) ALDH1A1MAPTLMNAS100BRAB9A
SCHEMBL13309938 0.88 CNR2 (0.60) ALDH1A1MAPTLMNAS100BTP53
SCHEMBL13309942 0.88 CNR2 (0.60) ALDH1A1MAPTLMNAS100BTP53
Acetamide SCHEMBL16335345 0.87 RECQL (0.59) ALDH1A1MAPTLMNAS100BGABRP
SCHEMBL17134428 0.85 ALDH1A1 (0.57) ALDH1A1MAPTLMNAS100BGABRP
SCHEMBL5545798 0.82 MEN1 (0.57) ALDH1A1MAPTLMNATP53CNR2
SCHEMBL31474389 0.82 MEN1 (0.57) ALDH1A1MAPTLMNATP53CNR2
SCHEMBL31474388 0.82 MEN1 (0.57) ALDH1A1MAPTLMNATP53CNR2
SCHEMBL13252856 0.81 ALDH1A1 (0.53) ALDH1A1MAPTLMNARAB9ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106431954-A Synthesis method of diazepam drug intermediate 2-chloracetamido-5-chlorobenzophenone 厦门莱恩斯特信息科技有限公司 2017-02-22 CN claimed
CN-105541653-A A synthetic method of a diazepam drug intermediate 2-chloroacetamido-5-chlorobenzophenone CHENGDU DONGDIAN AIER SCIENCE AND TECH CO LTD 2016-05-04 CN claimed
CN-106431954-A Synthesis method of diazepam drug intermediate 2-chloracetamido-5-chlorobenzophenone 厦门莱恩斯特信息科技有限公司 2017-02-22 CN disclosed
CN-105541653-A A synthetic method of a diazepam drug intermediate 2-chloroacetamido-5-chlorobenzophenone CHENGDU DONGDIAN AIER SCIENCE AND TECH CO LTD 2016-05-04 CN disclosed