Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12101028 | 0.73 | PLA2G4A (0.47) | PLA2G4ASMN1; SMN2 | |
| SCHEMBL6840495 | 0.73 | HSD17B10 (0.43) | PLA2G4ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28170691 | 0.72 | PLA2G4A (0.39) | PLA2G4ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31596034 | 0.72 | PLA2G4A (0.41) | PLA2G4ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21722413 | 0.72 | PLA2G4A (0.41) | PLA2G4ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12548426 | 0.70 | PLA2G4A (0.67) | PLA2G4A | |
| SCHEMBL28069678 | 0.70 | PLA2G4A (0.37) | PLA2G4ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10247168 | 0.69 | ALDH1A1 (0.39) | — | |
| SCHEMBL7555425 | 0.68 | XIAP (0.44) | PLA2G4ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12548427 | 0.68 | HSD17B10 (0.54) | PLA2G4ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105566324-A | Hydroxyl purine compound and application thereof | GOOD DOCTOR PHARMACEUTICAL GROUP CO LTD | 2016-05-11 | — | — | CN | disclosed |