Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.51 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.43 |
| ▸ | BCL6 | P41182 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | TAF1 | P21675 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28069741 | 0.87 | PGR (0.41) | BRD4EGLN1 | |
| SCHEMBL28069692 | 0.82 | ALDH1A1 (0.44) | BRD4CHRM3TAF1KDM4EALDH1A1 | |
| SCHEMBL28192074 | 0.82 | BRD4 (0.44) | BRD4CHRM3TAF1ALDH1A1 | |
| SCHEMBL28069693 | 0.76 | BRD4 (0.42) | BRD4CHRM3BRD9ALDH1A1 | |
| SCHEMBL28069745 | 0.75 | ALDH1A1 (0.43) | BRD4BRD9ALDH1A1 | |
| SCHEMBL28069747 | 0.75 | ALDH1A1 (0.49) | BRD4BRD9KDM4EALDH1A1GAA | |
| SCHEMBL28069746 | 0.74 | BRD4 (0.42) | BRD4CHRM3TAF1BRD9KDM4E | |
| SCHEMBL31019130 | 0.72 | GSK3B (0.60) | KAT6AKDM4EALDH1A1GAA | |
| SCHEMBL1544890 | 0.72 | GSK3B (0.60) | KAT6AKDM4EALDH1A1GAA | |
| SCHEMBL3920748 | 0.72 | BRD4 (0.55) | BRD4ADRA2CKDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105745193-B | Antimycotic oxo-dihydro pyridine carbohydrazide derivative | 株式会社大熊制药 | 2017-12-01 | — | — | CN | claimed |
| CN-105745193-A | Novel antifungal oxodihydropyridinecarbohydrazide derivative | 株式会社大熊制药 | 2016-07-06 | — | — | CN | claimed |
| CN-105745193-B | Antimycotic oxo-dihydro pyridine carbohydrazide derivative | 株式会社大熊制药 | 2017-12-01 | — | — | CN | disclosed |
| CN-105745193-A | Novel antifungal oxodihydropyridinecarbohydrazide derivative | 株式会社大熊制药 | 2016-07-06 | — | — | CN | disclosed |