Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | BCL9 | O00512 | 3/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28069745 | 0.87 | ALDH1A1 (0.43) | BRD4ALDH1A1MAPTL3MBTL1BCL9 | |
| SCHEMBL28069747 | 0.84 | ALDH1A1 (0.49) | BRD4ALDH1A1MAPTL3MBTL1BRD9 | |
| SCHEMBL28192074 | 0.84 | BRD4 (0.44) | BRD4ALDH1A1MAPTL3MBTL1CHRM3 | |
| SCHEMBL28069746 | 0.83 | BRD4 (0.42) | BRD4ALDH1A1MAPTL3MBTL1BRD9 | |
| SCHEMBL28069692 | 0.81 | ALDH1A1 (0.44) | BRD4ALDH1A1MAPTL3MBTL1CHRM3 | |
| SCHEMBL28069741 | 0.79 | PGR (0.41) | BRD4AR | |
| SCHEMBL28069689 | 0.76 | BRD4 (0.51) | BRD4ALDH1A1BRD9CHRM3 | |
| SCHEMBL24934110 | 0.70 | OGG1 (0.42) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL16672322 | 0.70 | BCL2L1 (0.47) | BRD4BRD9HDAC1HDAC2MAPK14 | |
| SCHEMBL16672348 | 0.69 | PTGS1 (0.48) | BRD4ALDH1A1MAPTL3MBTL1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105745193-B | Antimycotic oxo-dihydro pyridine carbohydrazide derivative | 株式会社大熊制药 | 2017-12-01 | — | — | CN | claimed |
| CN-105745193-A | Novel antifungal oxodihydropyridinecarbohydrazide derivative | 株式会社大熊制药 | 2016-07-06 | — | — | CN | claimed |
| CN-105745193-B | Antimycotic oxo-dihydro pyridine carbohydrazide derivative | 株式会社大熊制药 | 2017-12-01 | — | — | CN | disclosed |
| CN-105745193-A | Novel antifungal oxodihydropyridinecarbohydrazide derivative | 株式会社大熊制药 | 2016-07-06 | — | — | CN | disclosed |