Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.59 |
| ▸ | AR | P10275 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28070230 | 0.83 | ALDH1A1 (0.73) | CYP3A4KMT2AKDM4EMEN1LMNA | |
| 3-Methyl-2-Phenyl-4H-Chromen-4-One SCHEMBL694139 | 0.81 | ALDH1A1 (0.68) | ABCG2CYP3A4KMT2AKDM4EMEN1 | |
| SCHEMBL27767731 | 0.78 | GAA (0.54) | ABCG2CYP3A4KMT2AKDM4EMEN1 | |
| SCHEMBL29349443 | 0.78 | KMT2A (0.69) | ABCG2CYP3A4KMT2AKDM4EMEN1 | |
| SCHEMBL693914 | 0.78 | KMT2A (0.69) | ABCG2CYP3A4KMT2AKDM4EMEN1 | |
| SCHEMBL7703075 | 0.76 | PLA2G2A (0.73) | ABCG2CYP3A4KMT2AKDM4EMEN1 | |
| SCHEMBL28847414 | 0.76 | KMT2A (0.67) | ABCG2CYP3A4KMT2AKDM4EMEN1 | |
| SCHEMBL4634257 | 0.76 | KMT2A (0.67) | ABCG2CYP3A4KMT2AKDM4EMEN1 | |
| SCHEMBL31717956 | 0.76 | KMT2A (0.67) | ABCG2CYP3A4KMT2AKDM4EMEN1 | |
| SCHEMBL28162855 | 0.76 | KMT2A (0.67) | ABCG2CYP3A4KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111303111-B | Huang Jing near-infrared two-region dye, preparation method and fluorescence imaging application | 华东理工大学 | 2023-01-10 | — | — | CN | disclosed |
| CN-112940718-B | Cu2+Fluorescent covalent organic framework material and preparation method and application thereof | 齐齐哈尔大学 | 2022-06-17 | — | — | CN | disclosed |
| CN-111303111-A | Novel cyanine near-infrared two-region dye, preparation method and fluorescent imaging application | 华东理工大学 | 2020-06-19 | — | — | CN | disclosed |
| CN-105646463-A | Tacrine-dimethylamino flavone hybrid compounds and preparation method and application thereof | 河南大学 | 2016-06-08 | — | — | CN | disclosed |